- The youngest of the 10 Wayans siblings.
- Made his film debut in 1988's I'm Gonna Git You Sucka, which was written and directed by his brother Keenen Ivory Wayans.
- Was set to play Robin in Tim Burton's Batman Returns (1992), but the character was cut from the film. Three years later, he lost out on the chance to play the part in Batman Forever after Burton was replaced by Joel Schumacher, who cast Chris O'Donnell.
- Has appeared in PSA-like commercials for Dentyne's Safe Breath Alliance (SBA), a mock organization committed to educating Americans about the importance of practicing safe breath.
- Arnai Zackary Wayans — Daughter
- Nadia Wayans — Sister
- Shawn Wayans — Brother
- Angelica Zackary — Wife
- Dwayne Wayans — Brother
- Elvira Wayans — Sister
- Keenen Ivory Wayans — Brother
- Damon Wayans — Brother
- Shawn Howell Wayans — Son
- Elvira Wayans — Mother
- Howell Wayans — Father
- Diedre Wayans — Sister
- Kim Wayans — Sister
- Vonnie Wayans — Sister
- Attended Howard University, Washington, District of Columbia, United States
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